BDBM50608326 CHEMBL5275055

SMILES OC(=O)c1ccc(cc1)N1C(=O)\C(=C\c2ccc(cc2)[N+]([O-])=O)C=C1c1ccccc1

InChI Key InChIKey=MSVZBBATVMKDKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50608326   

TargetSignal transducer and activator of transcription 3(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50608326(CHEMBL5275055)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FLAG-tagged STAT3 (unknown origin) expressed in human NCI-H1299 cells assessed as reduction in DNA binding activity incubated for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50608326(CHEMBL5275055)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of STAT3 (unknown origin) stably expressed in human MDA-MB-231 cells incubated for 48 hrs by Luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50608326(CHEMBL5275055)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of recombinant YFP tagged STAT3 (127 to 688 residues) (unknown origin) incubated for 24 hrs by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed