BDBM50608080 CHEMBL5277519

SMILES Cc1ccc2c(ccnc2c1)-c1c(ncn1C)-c1c(C)cc(CN)cc1C

InChI Key InChIKey=ARHSYLADQLXDPH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50608080   

TargetHistone-lysine N-methyltransferase NSD3(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50608080(CHEMBL5277519)
Affinity DataKd:  1.66E+5nMAssay Description:Binding affinity to recombinant human NSD3 PWWP1 domain (247 to 398 residues) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50608080(CHEMBL5277519)
Affinity DataIC50: 203nMAssay Description:Antagonist activity against recombinant human GST-tagged NSD3 PWWP1 domain (247 to 398 residues) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed