BDBM50608077 CHEMBL5270736

SMILES CC1CN1c1cc(O)c2nc(N)sc2c1

InChI Key InChIKey=PHBIAWCGMOCBGF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50608077   

TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608077(CHEMBL5270736)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of NSD1 (unknown origin) measured after 4 hrs by MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608077(CHEMBL5270736)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of NSD1 (unknown origin) measured after 16 hrs by MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608077(CHEMBL5270736)
Affinity DataIC50: 1.40E+6nMAssay Description:Inhibition of NSD1 SET domain (1852 to 2105 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) preincubated for 1 hrs followed by HM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608077(CHEMBL5270736)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of N-terminal hexa-histidine tagged NSD1 SET domain (1852 to 2105 residues) (unknown origin) expressed in Escherichia coli incubated for 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608077(CHEMBL5270736)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminal hexa-histidine tagged NSD1 SET domain (1852 to 2105 residues) (unknown origin) expressed in Escherichia coli incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed