BDBM50608061 CHEMBL5279076

SMILES C\C(=N/OCc1cc(ccc1C#N)C(O)=O)c1ccc(OCc2c(onc2-c2ccccc2OC(F)(F)F)C2CC2)cc1Cl

InChI Key InChIKey=YQSSHFJUFMLIMK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50608061   

TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608061(CHEMBL5279076)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608061(CHEMBL5279076)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-transfected with CRE-Luc reporter plasmid assessed as receptor transactivation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed