BDBM50607928 CHEMBL5287531

SMILES CC(=O)Nc1cccc(c1)-c1ncnc2[nH]ccc12

InChI Key InChIKey=YAJKTHRIWKTLDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50607928   

TargetTyrosine-protein kinase JAK3(Human)
Research Centre For Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50607928(CHEMBL5287531)
Affinity DataIC50: 832nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 45 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Research Centre For Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50607928(CHEMBL5287531)
Affinity DataIC50: 832nMAssay Description:Inhibition of JAK3 (unknown origin) preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Research Centre For Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50607928(CHEMBL5287531)
Affinity DataIC50: 222nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed