BDBM50607925 CHEMBL5270221

SMILES NC(=O)C(=C\c1cc(cc(c1)C(F)(F)F)C(F)(F)F)\C#N

InChI Key InChIKey=PGZKKYMEBFZCMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607925   

TargetRibosomal protein S6 kinase alpha-3(Human)
Research Centre For Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50607925(CHEMBL5270221)
Affinity DataIC50: 399nMAssay Description:Inhibition of RSK2 (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Research Centre For Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50607925(CHEMBL5270221)
Affinity DataIC50: 56nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 45 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed