BDBM50607923 CHEMBL5274229

SMILES CC1CN(C(=O)Nc2ccc(Cl)c(Cl)c2)\C(S1)=N\c1cccc(F)c1

InChI Key InChIKey=BBFADOMAPZXJDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50607923   

TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50607923(CHEMBL5274229)
Affinity DataIC50: 310nMAssay Description:Inhibition of mTORC2 in human LN-229 cells assessed as decrease in phosphorylation of AKT at Ser473 level incubated for 24 hrs by immunoblot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed