BDBM50607758 CHEMBL5219991

SMILES CCOc1ccc2[C@@H](C)C(=O)N(C)C=C(c3cnn(C)c3)c2c1

InChI Key InChIKey=YYAYEFOQKNFTPU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50607758   

TargetBromodomain-containing protein 4(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50607758(CHEMBL5219991)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50607758(CHEMBL5219991)
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetC-C motif chemokine 2(Human)
Gsk

Curated by ChEMBL
LigandPNGBDBM50607758(CHEMBL5219991)
Affinity DataIC50: 20nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed