BDBM50607616 CHEMBL5220345::US11718589, Compound 12b

SMILES O=C(N1CCOCC1)c1ccc2nc(-c3ccccc3)c(nc2c1)-c1ccccc1

InChI Key InChIKey=XMOAXXRVOGXRCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607616   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50607616(CHEMBL5220345 | US11718589, Compound 12b)
Affinity DataIC50: 2.50E+3nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50607616(CHEMBL5220345 | US11718589, Compound 12b)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed