BDBM50607591 CHEMBL5219472

SMILES Clc1cccc(c1)C1(CCCC1)C(=O)N1CCC[C@@H]1C(=O)Nc1ccc2[nH]nnc2c1

InChI Key InChIKey=OQXKALXQYNBJIQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607591   

TargetHistone acetyltransferase p300(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607591(CHEMBL5219472)
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607591(CHEMBL5219472)
Affinity DataEC50:  3.98E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed