BDBM50607580 CHEMBL5218875

SMILES COc1ccc(NC(=O)[C@H]2CCCN2C(=O)C2(CCC2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=NUHVYWZIMVZPTE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607580   

TargetHistone acetyltransferase p300(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607580(CHEMBL5218875)
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607580(CHEMBL5218875)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed