BDBM50607571 CHEMBL5219570

SMILES C[C@@]1(CCCc2sc(N)c(C#N)c12)c1nc(no1)-c1ccc(N)cc1

InChI Key InChIKey=OTYSTCZFARVMKT-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50607571   

TargetGTPase KRas(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50607571(CHEMBL5219570)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity to KRAS G12V mutant (unknown origin) assessed as dissociation constant by HSQC NMR spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetGTPase KRas(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50607571(CHEMBL5219570)
Affinity DataKd: >2.00E+6nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) assessed as dissociation constant by HSQC NMR spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetGTPase KRas(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50607571(CHEMBL5219570)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed