BDBM50607565 CHEMBL5219175

SMILES CC1(CCCc2c1c(c(s2)N)C#N)C

InChI Key InChIKey=RANGIXHAOGTFIH-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607565   

TargetGTPase KRas(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50607565(CHEMBL5219175)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to KRAS G12V mutant (unknown origin) assessed as dissociation constant by HSQC NMR spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetGTPase KRas(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50607565(CHEMBL5219175)
Affinity DataKd:  1.50E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed