BDBM50607543 CHEMBL5220590

SMILES C[C@@H]1Cc2cc(cnc2N1)C(N)=O

InChI Key InChIKey=HLBSXLCCTVSVBK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50607543   

TargetNicotinamide N-methyltransferase(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50607543(CHEMBL5220590)
Affinity DataIC50: 42nMAssay Description:Inhibition of human NNMT measured after 20 mins by luminescence based methyltransferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNicotinamide N-methyltransferase(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50607543(CHEMBL5220590)
Affinity DataIC50: 38nMAssay Description:Inhibition of human NNMT in human K562 cells measured after 24 hrs by quantitative mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCytochrome P450 4B1(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50607543(CHEMBL5220590)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP450 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50607543(CHEMBL5220590)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed