BDBM50607515 CHEMBL5219013

SMILES C[C@H](C(=O)N(C)CC(O)(Cn1ccnc1)c1ccc(Cl)cc1)c1ccc(c(F)c1)-c1ccccc1

InChI Key InChIKey=JWWRFFTYPAHLAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607515   

TargetLanosterol 14-alpha demethylase(Yeast)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50607515(CHEMBL5219013)
Affinity DataIC50: 190nMAssay Description:Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as reduction in substrate consumption using lanosterol as substrate preincubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50607515(CHEMBL5219013)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of COX2 (unknown origin) assessed as reduction in PGF2alpha content using arachidonic acid as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed