BDBM50607442 CHEMBL5219348::US20250145576, Compound K2

SMILES CC(C)(C)CN(Cc1ccc(cc1)-c1ccccc1)c1nccc(n1)C#N

InChI Key InChIKey=TVEKAFPPBUQYEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50607442   

TargetCathepsin K(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607442(CHEMBL5219348 | US20250145576, Compound K2)
Affinity DataIC50: 235nMAssay Description:Inhibition of Cathepsin K (unknown origin) assessed as inhibition of AFC release using sequence LR labelled with AFC as substrate by fluorescence bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCathepsin S(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607442(CHEMBL5219348 | US20250145576, Compound K2)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Cathepsin S (unknown origin) assessed as inhibition of AFC release using sequence VVR labelled with AFC as substrate by fluorescence ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCathepsin B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607442(CHEMBL5219348 | US20250145576, Compound K2)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Cathepsin B (unknown origin) assessed as inhibition of AFC release using sequence RR labelled with AFC as substrate by fluorescence bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCathepsin K(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607442(CHEMBL5219348 | US20250145576, Compound K2)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent