BDBM50607105 CHEMBL5218728

SMILES CCCCNC(=O)COc1ccc2C(NC(=O)CCCOc3cc(c(cc3OC)C(C)O)[N+]([O-])=O)c3ccccc3CCc2c1

InChI Key InChIKey=VGHUFSKZTKPYED-UHFFFAOYSA-N

Data  2 Kd  1 EC50  2 Koff  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50607105   

LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataEC50: <5.00E+3nMAssay Description:Modulation of human Sirt3 (118 to 399 residues) deacetylation activity under non-steady state assessed as substrate deacetylation at low enzyme conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKoff:  20.1s-1Assay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant (Kon) by short DNA nano levers based switchSENSE microfluid b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKon:  0.220M-1s-1Assay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant (Koff) by short DNA nano levers based switchSENSE microfluid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant by short DNA nano levers based switchSENSE microfluid bio-chi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKoff:  70.9s-1Assay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant (Kon) of ternary complex using acetylated MnSOD peptide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKon:  0.162M-1s-1Assay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant (Koff) of ternary complex using acetylated MnSOD peptide as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607105(CHEMBL5218728)
Affinity DataKd:  1.26E+4nMAssay Description:Binding affinity to human Sirt3 (118 to 399 residues) assessed as dissociation constant of ternary complex using acetylated MnSOD peptide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed