BDBM50606726 CHEMBL5220911

SMILES CC(=O)N1CCN(CC1)c1cnc2ccc(cc2n1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1

InChI Key InChIKey=KGNNMSGRBVKSQP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50606726   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50606726(CHEMBL5220911)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606726(CHEMBL5220911)
Affinity DataIC50: 0.495nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606726(CHEMBL5220911)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606726(CHEMBL5220911)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606726(CHEMBL5220911)
Affinity DataIC50: 0.495nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed