BDBM50606724 CHEMBL5219124

SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncc(nc2c1)N1CCN(CC1)C(=O)CCOCCOCCOCCONC(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=VARVHYOTVXHELT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50606724   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50606724(CHEMBL5219124)
Affinity DataIC50: 53nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606724(CHEMBL5219124)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606724(CHEMBL5219124)
Affinity DataIC50: 467nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606724(CHEMBL5219124)
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606724(CHEMBL5219124)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed