BDBM50606505 CHEMBL5218990

SMILES COc1cc2ncnc(Sc3cccc(NC(=S)Nc4ccc(Br)c(c4)C(F)(F)F)c3)c2cc1OC

InChI Key InChIKey=AARRKLWESWJSEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50606505   

TargetEpidermal growth factor receptor(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50606505(CHEMBL5218990)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50606505(CHEMBL5218990)
Affinity DataIC50: 80nMAssay Description:Inhibition of VEGFR-2 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by caliper mobility shift assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed