BDBM50606475 CHEMBL3218002

SMILES ONC(=O)\C=C\c1ccn(c1)S(=O)(=O)c1ccc2ncnc(Nc3cccc(c3)C#C)c2c1

InChI Key InChIKey=XGSCWZVQRNHENL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50606475   

TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606475(CHEMBL3218002)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606475(CHEMBL3218002)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606475(CHEMBL3218002)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed