BDBM50606473 CHEMBL5220945

SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc(CNC(=O)CC(=O)NO)cc2)ncc1F

InChI Key InChIKey=LFWRZTGKNXDMJU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50606473   

TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606473(CHEMBL5220945)
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606473(CHEMBL5220945)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606473(CHEMBL5220945)
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606473(CHEMBL5220945)
Affinity DataIC50: 73nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606473(CHEMBL5220945)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Cdk4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed