BDBM50606239 CHEMBL5179874

SMILES COc1ccc(Cc2sc3COCCc3c2C(=O)N[C@@H](C)c2ccc(cc2)C(O)=O)cc1F

InChI Key InChIKey=AIDPPJKMDADILI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50606239   

TargetProstaglandin E2 receptor EP1 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606239(CHEMBL5179874)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human EP1 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606239(CHEMBL5179874)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human EP2 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606239(CHEMBL5179874)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human EP3 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606239(CHEMBL5179874)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human EP4 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed