BDBM50606218 CHEMBL5181722

SMILES C[C@H](NC(=O)c1c(CCc2ccc(F)cc2)sc2CCCc12)c1ccc(cc1)C(O)=O

InChI Key InChIKey=UFWXTNXFYIFXLF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50606218   

TargetProstaglandin E2 receptor EP1 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606218(CHEMBL5181722)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human EP1 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606218(CHEMBL5181722)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human EP2 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606218(CHEMBL5181722)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human EP3 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606218(CHEMBL5181722)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human EP4 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50606218(CHEMBL5181722)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at mouse EP4 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed