BDBM50605982 CHEMBL5170949

SMILES CC(C)[C@@H](N(CCCNC(=O)CCCCCCCCN1CCN(CC1)S(=O)(=O)c1ccc(NC(=S)NCc2cccnc2)cc1)C(=O)c1ccc(C)cc1)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1

InChI Key InChIKey=LZCAADBODOWVEZ-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605982   

TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50605982(CHEMBL5170949)
Affinity DataIC50: 23nMAssay Description:Inhibition of NAMPT (unknown origin) measured after 90 mins by measuring fluorescence intensityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50605982(CHEMBL5170949)
Affinity DataKd:  993nMAssay Description:Binding affinity to LC3B (unknown origin) assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50605982(CHEMBL5170949)
Affinity DataIC50: 40nMAssay Description:Induction of NAMPT degradation in human A2780 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed