BDBM50605880 CHEMBL5174424

SMILES Cc1onc(c1COc1ccc2C(=O)N(CC3CCCS3(=O)=O)CCc2n1)-c1ccc(F)cc1

InChI Key InChIKey=SDNJJSNWVUZIFI-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605880   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Gedeon Richter

Curated by ChEMBL

LigandBDBM50605880(CHEMBL5174424)Copy SMILESCopy InChI

Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/25/2023
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL

LigandBDBM50605880(CHEMBL5174424)Copy SMILESCopy InChI

Affinity DataKi:  23nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/25/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL