BDBM50605685 CHEMBL5188296

SMILES Oc1ccc(Cl)c(c1)C(=O)N1CCC(Cc2cccc(Oc3ccc(cn3)C(F)(F)F)c2)CC1

InChI Key InChIKey=LTXWYCQKCIHXJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605685   

TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50605685(CHEMBL5188296)
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate incubated for 30 mins by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50605685(CHEMBL5188296)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed