BDBM50605384 CHEMBL5175977

SMILES Cc1cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)cc(CS(=O)(=O)c2ccccc2)c1Br

InChI Key InChIKey=HHZHOYGIUZUEII-UHFFFAOYSA-N

Data  25 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50605384   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInsulin receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Insulin receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ACK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEphrin type-B receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SPHK2 (unknown origin) using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSphingosine kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 20nMAssay Description:Inhibition of SPHK1 (unknown origin) using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed