BDBM50605139 CHEMBL5184577

SMILES CC(C)(C)C[C@@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@@]1(CNc1cccc(c1)C(O)=O)c1ccc(Cl)cc1F)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=GUTIKUOFJAOKSI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50605139   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50605139(CHEMBL5184577)
Affinity DataKi:  3.60nMAssay Description:Displacement of 5-FAM labeled PDI peptide from MDM2 (1 to 118 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed