BDBM50605104 CHEMBL5180980

SMILES C[C@@H](c1ccc(Cl)cc1Cl)n1cnc(c1-c1c([nH]c2cc(Cl)ccc12)C(=O)Nc1cc(ccc1N1CCC(CC1)N1CCCOC1=O)C(O)=O)-c1ccccc1

InChI Key InChIKey=GSVXCPWDMIREAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605104   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50605104(CHEMBL5180980)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human MDM2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein Mdm4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50605104(CHEMBL5180980)
Affinity DataIC50: 17nMAssay Description:Inhibition of human MDM4 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed