BDBM50605009 CHEMBL5209354

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C(C)(C)c5c(C[C@]4(C)[C@@]3([H])CC[C@]12C)ncn5C(C)=O)[C@H](C)CC(=O)N1CCOCC1

InChI Key InChIKey=CHGPLBNMJBDSJM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50605009   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Chinese hamster)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605009(CHEMBL5209354)
Affinity DataEC50:  280nMAssay Description:Induction of degradation of hamster HMGCR (TM1-8)-GFP (1 to 346 residues) transfected in CHO-7 cells incubated for 16 hrs in sterol-depleted medium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed