BDBM50604793 CHEMBL5169990

SMILES C[C@@H](O)[C@H](N)C(=O)N[C@@H](CNC(=O)CCn1cnc2cc(Cl)c(Cl)cc2c1=O)c1cccc(c1)-c1ccc2C(=O)NCc2c1

InChI Key InChIKey=SXLUECWAPXFDGD-UHFFFAOYSA-N

Data  1 IC50  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50604793   

TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  35nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant by isothermal titration ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  75nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of ATP by isot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  290nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of L-threonine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  44nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of glycine by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  166nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of tRNA Threon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  37nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of tRNA Leucin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed