BDBM50604736 CHEMBL5191984

SMILES CC(=O)O[C@H]1CCc2c(ccc3-c4occ(CO)c4C(=O)C(=O)c23)C1(C)C

InChI Key InChIKey=IIKBEPVPOUPRPM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604736   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604736(CHEMBL5191984)
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate and measured after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604736(CHEMBL5191984)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of recombinant human TDO assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate and measured after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604736(CHEMBL5191984)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate by absorbanc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604736(CHEMBL5191984)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of TDO in human HEK293 cells assessed as reduction in kynurenine formation using L-tryptophan as substrate by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed