BDBM50604355 CHEMBL5207988

SMILES Cc1nc2ccc(cc2n1C)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O

InChI Key InChIKey=FXJVNDJFCCCBEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50604355   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Agios Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50604355(CHEMBL5207988)
Affinity DataIC50: 21nMAssay Description:Inhibition of MT2A in MTAP-null human HCT-116 cells after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed