BDBM50604333 CHEMBL5186703

SMILES OC(=O)C(=O)C(=C\c1ccccc1C(F)(F)F)\c1ccc2ccccc2n1

InChI Key InChIKey=WAWISSQZPGUGIC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50604333   

TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50604333(CHEMBL5186703)
Affinity DataIC50: 4.81E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) assessed as residual activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50604333(CHEMBL5186703)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) in presence of DTT by PAINS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50604333(CHEMBL5186703)
Affinity DataIC50: 5.16E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) in presence of BSA by PAINS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed