BDBM50604328 CHEMBL5180795

SMILES CC(C)(C)NC(=O)CC[C@H](NC(=O)CCNC(=O)CCl)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)NCc1cccc2ccccc12

InChI Key InChIKey=SZXRRFKYQZMKHS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50604328   

TargetProteasome subunit beta type-8(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604328(CHEMBL5180795)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604328(CHEMBL5180795)
Affinity DataIC50: 572nMAssay Description:Inhibition of 20S proteasome subunit beta-5c (unknown origin) using Ac-WLA-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604328(CHEMBL5180795)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-1i (unknown origin) using Ac-PAL-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604328(CHEMBL5180795)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-1c (unknown origin) using Z-LLE-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-10(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604328(CHEMBL5180795)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-2i (unknown origin) using Ac-KQL-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-4(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604328(CHEMBL5180795)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-2c (unknown origin) using Ac-KQL-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed