BDBM50604128 CHEMBL5177378

SMILES ClCCCC(=O)Nc1ccc2ncnc(Nc3ccc4[nH]ccc4c3)c2c1

InChI Key InChIKey=SUPHEZJBHOETQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604128   

TargetEpidermal growth factor receptor(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604128(CHEMBL5177378)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of wild-type EGFR (14 to 721 residues) (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604128(CHEMBL5177378)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human EGFR L858R/T790M double mutant using GGMEDIYFEFMGG as substrate in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed