BDBM50604038 CHEMBL5206811::US20230312529, Compound 6c

SMILES Cc1cnc(Nc2ccc(cc2)N2CCC(F)(F)CC2)nc1Nc1ccc2cn[nH]c2c1

InChI Key InChIKey=GZYVOINWLCLXNA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50604038   

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 81nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 103nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 540nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 81nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 103nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 476nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 72nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 1.00E+3nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 74nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604038(CHEMBL5206811 | US20230312529, Compound 6c)
Affinity DataIC50: 91nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed