BDBM50604034 CHEMBL5187885::US20230312529, Compound 6d

SMILES Cc1cnc(Nc2ccc(cc2)N2CCS(=O)(=O)CC2)nc1Nc1ccc2cn[nH]c2c1

InChI Key InChIKey=MDLHMWDJSUJDBH-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50604034   

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 66.6nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 70.3nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 117nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 46nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 39nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 186nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 99nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 619nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 42nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604034(CHEMBL5187885 | US20230312529, Compound 6d)
Affinity DataIC50: 41nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed