BDBM50603977 CHEMBL5189523

SMILES COc1cc(F)ccc1-c1cnc2sc(nn12)N1CCC(C)(N)CC1

InChI Key InChIKey=KUQLTAUECPDOLQ-UHFFFAOYSA-N

Data  2 IC50  7 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50603977   

TargetSerine/threonine-protein kinase haspin(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of hERG by Qpatch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to human CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataKd:  600nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to human KITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to human PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataKd:  7.40E+3nMAssay Description:Binding affinity to human PIM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to human PIM3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50603977(CHEMBL5189523)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to human HASPINMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed