BDBM50603914 CHEMBL5176847::US11873292, Compound A6

SMILES O=S(=O)(N1CCc2cc(ccc12)C1CC1NCc1ccncc1)c1ccccc1

InChI Key InChIKey=FNMBFNWGLJARDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50603914   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603914(CHEMBL5176847 | US11873292, Compound A6)
Affinity DataIC50: 261nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603914(CHEMBL5176847 | US11873292, Compound A6)
Affinity DataIC50: 2.61E+5nMAssay Description:Inhibition of N-terminal His/GST-tagged human LSD1 (172 to 852 residues) expressed in expressed in baculovirus infected insect cells using biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed