BDBM50603895 CHEMBL5179395

SMILES [O-]P(=O)(OC1=Cc2c(Cl)cccc2Sc2ccccc12)OC1=Cc2c(Cl)cccc2Sc2ccccc12

InChI Key InChIKey=HKMAUJVXUQESRC-UHFFFAOYSA-M

Data  3 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50603895   

TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in 6-OAU induced intracellular calcium resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells assessed as reversal of 6-OAU induced inhibition of forskolin induced intracellular cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataIC50: 273nMAssay Description:Antagonist activity at mouse GPR84 expressed in HEK293 cells assessed as reduction in 6-OAU induced intracellular calcium response preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataEC50:  2.84E+4nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as right shift in 3-OH-C12-induced calcium response curv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataEC50:  8.42E+4nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as right shift in 3-OH-C12-induced calcium response curv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataEC50:  4.87E+5nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as right shift in 3-OH-C12-induced calcium response curv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataEC50:  1.13E+3nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as right shift in 6-OAU-induced calcium response curve b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataEC50:  1.79E+3nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as right shift in 6-OAU-induced calcium response curve b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataEC50:  3.73E+3nMAssay Description:Antagonist activity at human GPR84 expressed in HEK293 cells co-expressing Galpha16 assessed as right shift in 6-OAU-induced calcium response curve b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed