BDBM50603549 CHEMBL5203882

SMILES Brc1ccc(cc1)-c1nc2ccc(Br)cn2n1

InChI Key InChIKey=METAKUVFAGUKGU-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50603549   

TargetAryl hydrocarbon receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG channel in HEK293 cells by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed