BDBM50603512 CHEMBL5177475

SMILES CC(C)N(Cc1ccc(cc1)C(=O)NO)S(=O)(=O)c2cc(c(c(c2F)F)F)F

InChI Key InChIKey=SJWJGLIJTRUXIZ-UHFFFAOYSA-N

Data  1 KI  11 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50603512   

TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC3 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 6nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC8 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC11 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC1 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 316nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC4 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC5 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC7 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC9 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC10 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to full length human recombinant HDAC6 expressed in Sf9 baculovirus system assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed