BDBM50603485 CHEMBL5172647

SMILES COc1cc2nc3CCCCc3c(N3CCOCC3)c2cc1OC

InChI Key InChIKey=XAPKYBVMPJHUOI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50603485   

TargetAmyloid-beta precursor protein(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50603485(CHEMBL5172647)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of amyloid beta (1 to 42 ) (unknown origin) self aggregation measured after 3 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50603485(CHEMBL5172647)
Affinity DataIC50: 767nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant BuChE (29 to 602 residues) using butyrylthiocholine iodide as substrate preincubated for 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50603485(CHEMBL5172647)
Affinity DataIC50: 62nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant AChE (32 to 614 residues) expressed in HEK293 cells using acetylthiocholine iodide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed