BDBM50603136 CHEMBL5170470

SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C([O-])=O

InChI Key InChIKey=YYBOLPLTQDKXPM-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50603136   

TargetSolute carrier family 22 member 6(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603136(CHEMBL5170470)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by incubation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603136(CHEMBL5170470)
Affinity DataIC50: 170nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50603136(CHEMBL5170470)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells membrane vesicles assessed as inhibition of ATP-induced 14C-uric acid uptake preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed