BDBM50603134 CHEMBL5202967
SMILES [O-]C(=O)c1ccccc1CSc1ccncc1Nc1ccc(C#N)c2ccccc12
InChI Key InChIKey=KGXQVNQQKUPQGI-UHFFFAOYSA-M
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50603134
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by incubation ...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of URAT1 (unknown origin)-mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate preincubated for 30 min...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells membrane vesicles assessed as inhibition of ATP-induced 14C-uric acid uptake preincuba...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 9(Human)
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of GLUT9 (unknown origin) expressed in HEK293T cells assessed as inhibition of uric acid-induced current by whole cell patch clamp techniq...More data for this Ligand-Target Pair