BDBM50602947 CHEMBL5181357

SMILES Fc1ccc(CN2CCOc3cc(ccc3C2=O)-c2cnc3[nH]ccc3c2)cc1

InChI Key InChIKey=UVLOISNMRLZTPF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50602947   

TargetTRAF2 and NCK-interacting protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602947(CHEMBL5181357)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant TNIK (1 to 367 residues) using RLGRDKYKTLRQIRQ as substrate in presence of ATP incubated for 40 mins by radiometric b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602947(CHEMBL5181357)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FLT4 (800 to end residues) using GGEEEEYFELVKKKK as substrate in presence of ATP incubated for 40 mins by radiometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602947(CHEMBL5181357)
Affinity DataIC50: 191nMAssay Description:Inhibition of human recombinant FLT1 (783 to end residues) using KKKSPGEYVNIEFG as substrate in presence of ATP incubated for 40 mins by radiometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602947(CHEMBL5181357)
Affinity DataIC50: 441nMAssay Description:Inhibition of full length human recombinant DRAK1 using KKLNRTLSFAEPG as substrate in presence of ATP incubated for 40 mins by radiometric based scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAurora kinase A(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602947(CHEMBL5181357)
Affinity DataIC50: 517nMAssay Description:Inhibition of full length human recombinant AURORA-A using LRRASLG as substrate in presence of ATP incubated for 40 mins by radiometric based scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHexokinase-4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602947(CHEMBL5181357)
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of human recombinant GCK (1 to 473 residues) using myelin basic protein as substrate in presence of ATP incubated for 40 mins by radiometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602947(CHEMBL5181357)
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of human MLK3 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed