BDBM50602885 CHEMBL5193906

SMILES CC1(CCN(CC1)Cc2ccn3c2c(ncn3)Nc4cc(cc(c4)Br)O)N

InChI Key InChIKey=DBMRETDBROLHGL-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50602885   

TargetTau-tubulin kinase 1(Human)
Csic

Curated by ChEMBL
LigandPNGBDBM50602885(CHEMBL5193906)
Affinity DataIC50: 120nMAssay Description:Inhibition of TTBK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTau-tubulin kinase 2(Human)
Csic

Curated by ChEMBL
LigandPNGBDBM50602885(CHEMBL5193906)
Affinity DataIC50: 170nMAssay Description:Inhibition of TTBK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTau-tubulin kinase 1(Human)
Csic

Curated by ChEMBL
LigandPNGBDBM50602885(CHEMBL5193906)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)