BDBM50602859 CHEMBL5195570

SMILES NCCCc1nc(c(s1)-c1ccnc(N)n1)-c1cccc(NS(=O)(=O)c2cc(F)ccc2F)c1F

InChI Key InChIKey=NEZWQTPIFLCMQJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50602859   

TargetSerine/threonine-protein kinase B-raf(Human)
Cnrs

Curated by ChEMBL

LigandBDBM50602859(CHEMBL5195570)Copy SMILESCopy InChI

Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal His-tagged human recombinant B-Raf V600E mutant (448 to 723 residues) expressed in Escherichia coli BL21 (DE3) by Lanthascre...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
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TargetNuclear receptor subfamily 1 group I member 2(Human)
Cnrs

Curated by ChEMBL

LigandBDBM50602859(CHEMBL5195570)Copy SMILESCopy InChI

Affinity DataEC50: >3.00E+4nMAssay Description:Transactivation of Gal4-tagged human PXR transfected in human HeLa cells preincubated for 16 hrs followed by luciferin addition and measured after 10...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
Copy BDB DOIPubMed
Copy reaction URL